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1

NAD+ and sirtuins in aging and disease

Imai, Shin-ichiro, Guarente, Leonard

Journal:

Trends in Cell Biology

Year:

2014

Language:

english

File:

PDF, 617 KB

english, 2014

2

NAD + Intermediates: The Biology and Therapeutic Potential of NMN and NR

Yoshino, Jun, Baur, Joseph A., Imai, Shin-ichiro

Journal:

Cell Metabolism

Year:

2017

Language:

english

File:

PDF, 1.64 MB

english, 2017

3

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

de Picciotto, Natalie E., Gano, Lindsey B., Johnson, Lawrence C., Martens, Christopher R., Sindler, Amy L., Mills, Kathryn F., Imai, Shin-ichiro, Seals, Douglas R.

Journal:

Year:

2016

Language:

english

File:

PDF, 666 KB

english, 2016

4

It takes two to tango: NAD+ and sirtuins in aging/longevity control

Imai, Shin-ichiro, Guarente, Leonard

Journal:

npj Aging and Mechanisms of Disease

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

5

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

Jun Yoshino, Kathryn F. Mills, Myeong Jin Yoon, Shin-ichiro Imai

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 2.09 MB

english, 2011

6

The brain, sirtuins, and ageing

Satoh, Akiko, Imai, Shin-ichiro, Guarente, Leonard

Journal:

Nature Reviews Neuroscience

Year:

2017

Language:

english

File:

PDF, 663 KB

english, 2017

7

The NAD World 2.0: the importance of the inter-tissue communication mediated by NAMPT/NAD+/SIRT1 in mammalian aging and longevity control

Imai, Shin-ichiro

Journal:

npj Systems Biology and Applications

Year:

2016

Language:

english

File:

PDF, 1.31 MB

english, 2016

8

NAD+ biosynthesis, aging, and disease

Johnson, Sean, Imai, Shin–ichiro

Journal:

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

9

“Clocks” in the NAD World: NAD as a metabolic oscillator for the regulation of metabolism and aging

Shin-ichiro Imai

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2010

Language:

english

File:

PDF, 414 KB

english, 2010

10

The two-process model of cellular aging

Hiroaki Kitano, Shin-ichiro Imai

Journal:

Experimental Gerontology

Year:

1998

Language:

english

File:

PDF, 540 KB

english, 1998

11

A Clock Ticks in Pancreatic β Cells

Jun Yoshino, Shin-ichiro Imai

Journal:

Cell Metabolism

Year:

2010

Language:

english

File:

PDF, 128 KB

english, 2010

12

Mitochondrial SIRT3: A New Potential Therapeutic Target for Metabolic Syndrome

Jun Yoshino, Shin-ichiro Imai

Journal:

Year:

2011

Language:

english

File:

PDF, 136 KB

english, 2011

13

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Shin-ichiro Imai, Leonard Guarente

Journal:

Trends in Pharmacological Sciences

Year:

2010

Language:

english

File:

PDF, 351 KB

english, 2010

14

Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH

Satoh, Akiko, Brace, Cynthia S., Rensing, Nick, Cliften, Paul, Wozniak, David F., Herzog, Erik D., Yamada, Kelvin A., Imai, Shin-ichiro

Journal:

Cell Metabolism

Year:

2013

Language:

english

File:

PDF, 3.76 MB

english, 2013

15

Systemic regulation of mammalian ageing and longevity by brain sirtuins

Satoh, Akiko, Imai, Shin-ichiro

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 394 KB

english, 2014

16

Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes

Imai, Shin-ichiro

Journal:

Frontiers in Bioscience

Year:

2009

Language:

english

File:

PDF, 374 KB

english, 2009

17

Slc12a8 is a nicotinamide mononucleotide transporter

Grozio, Alessia, Mills, Kathryn F., Yoshino, Jun, Bruzzone, Santina, Sociali, Giovanna, Tokizane, Kyohei, Lei, Hanyue Cecilia, Cunningham, Richard, Sasaki, Yo, Migaud, Marie E., Imai, Shin-ichiro

Journal:

Nature Metabolism

Year:

2019

Language:

english

File:

PDF, 1.88 MB

english, 2019

18

Assimilation and contrast in optical illusions

TAKUO GOTO, ICHIRO UCHIYAMA, AKIRA IMAI, SHIN’YA TAKAHASHI, TAKASHI HANARI, SHINJI NAKAMURA, HIROYUKI KOBARI

Journal:

Japanese Psychological Research

Year:

2007

Language:

english

File:

PDF, 177 KB

english, 2007

19

A Randomized Controlled Trial of Therapeutic Exercise for Clicking Due to Disk Anterior Displacement with Reduction in the Temporomandibular Joint

Yoda, Tetsuya, Sakamoto, Ichiro, Imai, Hideki, Honma, Yoshinobu, Shinjo, Yu, Takano, Atsushi, Tsukahara, Hiroyasu, Morita, Shin, Miyamura, Juichi, Yoda, Yasushi, Sasaki, Yoshiyuki, Tomizuka, Ken, Taka

Journal:

Year:

2003

Language:

english

File:

PDF, 1.51 MB

english, 2003

20

Viscoelastic Behavior of Surfactant Threadlike Micellar Solutions: Effect of Additives 3

Shin-ichiro Imai, Toshiyuki Shikata

Journal:

Journal of Colloid and Interface Science

Year:

2001

Language:

english

File:

PDF, 93 KB

english, 2001

21

The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance

Shin-ichiro Imai

Journal:

Cell Biochemistry and Biophysics

Year:

2009

Language:

english

File:

PDF, 395 KB

english, 2009

22

Simultaneous determination of zonisamide, carbamazepine and carbamazepine-10,11-epoxide in infant serum by high-performance liquid chromatography

Terumitsu Yoshida, Koichi Imai, Sumiko Motohashi, Shin-ichiro Hamano, Masato Sato

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2006

Language:

english

File:

PDF, 214 KB

english, 2006

23

Preparation of polyimide Langmuir-Blodgett films possessing a triphenylamine unit and their application to photodiodes

Yasunari Nishikata, Shin-ichiro Fukui, Masa-aki Kakimoto, Yoshio Imai, Katsuhiko Nishiyama, Masamichi Fujihira

Journal:

Thin Solid Films

Year:

1992

Language:

english

File:

PDF, 221 KB

english, 1992

24

Transcortical sensory aphasia following the unilateral left thalamic infarction— A case report

Maeshima, Shin-ichiro, Komai, Norihiko, Kinoshita, Yasunobu, Ueno, Masami, Nakai, Ekini, Naka, Yutaka, Tsuji, Naoki, Imai, Harumichi, Kido, Takuhei

Journal:

Journal of Neurolinguistics

Year:

1992

Language:

english

File:

PDF, 1.67 MB

english, 1992

25

Effects of selective logging on tree species diversity and composition of Bornean tropical rain forests at different spatial scales

Nobuo Imai, Tatsuyuki Seino, Shin-ichiro Aiba, Masaaki Takyu, Jupiri Titin and Kanehiro Kitayama

Journal:

Year:

2012

Language:

english

File:

PDF, 2.02 MB

english, 2012

26

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

Mills, Kathryn F., Yoshida, Shohei, Stein, Liana R., Grozio, Alessia, Kubota, Shunsuke, Sasaki, Yo, Redpath, Philip, Migaud, Marie E., Apte, Rajendra S., Uchida, Koji, Yoshino, Jun, Imai, Shin-ichiro

Journal:

Cell Metabolism

Year:

2016

Language:

english

File:

PDF, 3.14 MB

english, 2016

27

The Development of Three-Dimensional Aerodynamic Design Blades for Turbines.

TANUMA, Tadashi, NAGAO, Shin-ichiro, SAKAMOTO, Taro, IKEDA, Nobukazu, MATSUDA, Minoru, IMAI, Ken-ichi

Journal:

JSME International Journal Series B

Year:

1998

File:

PDF, 2.11 MB

1998

28

The Pathophysiological Significance of NAD+ in the Regulation of Metabolism in Mammals and Its Therapeutic Potential

YOSHINO, Jun, IMAI, Shin-ichiro

Journal:

KAGAKU TO SEIBUTSU

Year:

2013

File:

PDF, 1.01 MB

2013

29

A simple method for the quantification of famotidine in human plasma and urine by paired-ion high performance liquid chromatography

Yasuhiko Imai, Shin-Ichiro Kobayashi

Journal:

Biomedical Chromatography

Year:

1992

Language:

english

File:

PDF, 212 KB

english, 1992

30

ChemInform Abstract: Structure, Magnetism, and Ionic Conductivity of the Gigantic {Mo176}-Wheel Assembly: Na15Fe3Co16 [Mo176O528H3(H2O)80] Cl27·450H2O.

Hiroyuki Imai, Tomoyuki Akutagawa, Fumito Kudo, Mitsuhiro Ito, Kazuhiro Toyoda, Shin-ichiro Noro, Leroy Cronin, Takayoshi Nakamura

Journal:

Year:

2009

File:

PDF, 18 KB

2009

31

Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation

Motonobu Watanabe, Souichi Adachi, Hiroshi Matsubara, Tsuyoshi Imai, Yoshihiro Yui, Yasuhiro Mizushima, Yoshimi Hiraumi, Ken-ichiro Watanabe, Yuri Kamitsuji, Shin-ya Toyokuni, Hajime Hosoi, Toru Sugim

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 2.34 MB

english, 2009

32

Application of high-performance liquid chromatography with a chemiluminescence detection system to determine catecholamines in urine

Shin-Ichiro Kobayashi, Jun Sekino, Kazumasa Honda, Kazuhiro Imai

Journal:

Analytical Biochemistry

Year:

1981

Language:

english

File:

PDF, 443 KB

english, 1981

33

Effect of backbone structures of polysilanes on the photooxidation reaction

Keiji Kabeta, Kiyoaki Shuto, Shin-ichiro Sugi, Takafumi Imai

Journal:

Year:

1996

Language:

english

File:

PDF, 588 KB

english, 1996

34

Effect of Carbon Ion Radiotherapy for Sacral Chordoma: Results of Phase I-II and Phase II Clinical Trials

Reiko Imai, Tadashi Kamada, Hiroshi Tsuji, Shinji Sugawara, Itsuko Serizawa, Hirohiko Tsujii, Shin-ichiro Tatezaki

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 396 KB

english, 2010

35

Abnormal Li diffusion in β-LiGa by the formation of defect complex

Sun-Chan Jeong, Ichiro Katayama, Hirokane Kawakami, Yutaka Watanabe, Hironobu Ishiyama, Nobuaki Imai, Yoshikazu Hirayama, Hiroari Miyatake, Masao Sataka, Hiroyuki Sugai, Satoru Okayasu, Shin-Ichi Ichi

Journal:

Solid State Ionics

Year:

2009

Language:

english

File:

PDF, 362 KB

english, 2009

36

Viscoelastic behavior of surfactant threadlike micellar solutions: effects of additives, 4

Toshiyuki Shikata, Mamoru Shiokawa, Shin-ichiro Imai

Journal:

Journal of Colloid and Interface Science

Year:

2003

Language:

english

File:

PDF, 415 KB

english, 2003

37

Analog LSI neuron model inspired by biological excitable membrane

Shin'Ichiro Kanoh, Makoto Imai, Nozomu Hoshimiya

Journal:

Systems and Computers in Japan

Year:

2005

Language:

english

File:

PDF, 507 KB

english, 2005

38

Longer transplanted heart allograft survival in rats without immunosuppressants after intrathymic myocardial cell inoculation in the neonatal period

Kazuhiro Seo, Shin-ichiro Imamura, Yoshiko Ohta, Toshio Nishikawa, Yasuharu Imai

Journal:

Heart and Vessels

Year:

1993

Language:

english

File:

PDF, 507 KB

english, 1993

39

Discovery and characterization ofd-phenylserine deaminase fromArthrobactersp. TKS1

Hisashi Muramatsu, Yuri Suzuki, Takeshi Imai, Sakuko Ueshima, Jun Ozaki, Yuji Matsui, Shin-ichiro Kato, Kouhei Ohnishi, Norihiro Kimoto, Hiroaki Yamamoto, Shinji Nagata

Journal:

Applied Microbiology and Biotechnology

Year:

2011

Language:

english

File:

PDF, 750 KB

english, 2011

40

Extractives ofQuercus crispulasapwood infected by the pathogenic fungiRaffaelea quercivoraI: comparison of sapwood extractives from noninfected and infected samples

Kayoko Imai, Tohru Mitsunaga, Hiroyuki Takemoto, Toshihiro Yamada, Shin-ichiro Ito, Hideo Ohashi

Journal:

Journal of Wood Science

Year:

2009

Language:

english

File:

PDF, 474 KB

english, 2009

41

Measurement of self-diffusion coefficients in Li ionic conductors by using the short-lived radiotracer of8Li

Sun-Chan Jeong, Ichiro Katayama, Hirokane Kawakami, Yutaka Watanabe, Hironobu Ishiyama, Nobuaki Imai, Yoshikazu Hirayama, Hiroari Miyatake, Masao Sataka, Satoru Okayasu, Hiroyuki Sugai, Shin-Ichi Ichi

Journal:

Journal of Phase Equilibria and Diffusion

Year:

2005

Language:

english

File:

PDF, 192 KB

english, 2005

42

Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma

Keichiro Mihara, Kazuyoshi Yanagihara, Misato Takigahira, Akira Kitanaka, Chihaya Imai, Joyeeta Bhattacharyya, Takanori Kubo, Yoshifumi Takei, Shin’ichiro Yasunaga, Yoshihiro Takihara, Akiro Kimura

Journal:

British Journal of Haematology

Year:

2010

Language:

english

File:

PDF, 587 KB

english, 2010

43

Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice

Kathryn Moynihan Ramsey, Kathryn F. Mills, Akiko Satoh, Shin-ichiro Imai

Journal:

Year:

2008

Language:

english

File:

PDF, 235 KB

english, 2008

44

Is Sirt1 a miracle bullet for longevity?

Shin-ichiro Imai

Journal:

Year:

2007

Language:

english

File:

PDF, 72 KB

english, 2007

45

A nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expression

Andrew A. Grimm, Cynthia S. Brace, Ting Wang, Gary D. Stormo, Shin-Ichiro Imai

Journal:

Year:

2011

Language:

english

File:

PDF, 593 KB

english, 2011

46

10.1038/35001622

Guarente, Leonard, Imai, Shin-ichiro, Armstrong, Christopher M., Kaeberlein, Matt

Journal:

Year:

2000

Language:

english

File:

PDF, 503 KB

english, 2000

47

Roles for host and tumor angiotensin II type 1 receptor in tumor growth and tumor-associated angiogenesis

Imai, Nozomi, Hashimoto, Tatsuo, Kihara, Minoru, Yoshida, Shin-ichiro, Kawana, Ichiro, Yazawa, Takuya, Kitamura, Hitoshi, Umemura, Satoshi

Journal:

Laboratory Investigation

Year:

2006

Language:

english

File:

PDF, 414 KB

english, 2006

48

Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme

Wang, Tao, Zhang, Xiangbin, Bheda, Poonam, Revollo, Javier R, Imai, Shin-ichiro, Wolberger, Cynthia

Journal:

Nature Structural and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 296 KB

english, 2006

49

FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells

Imai, Tsuyoshi, Adachi, Souichi, Nishijo, Koichi, Ohgushi, Masatoshi, Okada, Masayuki, Yasumi, Takahiro, Watanabe, Ken-ichiro, Nishikomori, Ryuta, Nakayama, Tomitaka, Yonehara, Shin

Journal:

Year:

2003

Language:

english

File:

PDF, 437 KB

english, 2003

50

Impact of carbon ion radiotherapy for unresectable osteosarcoma of the trunk

Akira Matsunobu, Reiko Imai, Tadashi Kamada, Takeshi Imaizumi, Hiroshi Tsuji, Hirohiko Tsujii, Yoshiyuki Shioyama, Hiroshi Honda, Shin-ichiro Tatezaki, for the Working Group for Bone, Soft Tissue Sarc

Journal:

Year:

2012

Language:

english

File:

PDF, 1022 KB

english, 2012